On Heteropolymer Shape Dynamics
نویسندگان
چکیده
منابع مشابه
On Heteropolymer Shape Dynamics
We investigate the time evolution of the heteropolymer model introduced by Iori, Marinari and Parisi to describe some of the features of protein folding mechanisms. We study how the (folded) shape of the chain evolves in time. We find that for short times the mean square distance (squared) between chain configurations evolves according to a power law, D ∼ tν . We discuss the influence of the qu...
متن کاملRandom heteropolymer dynamics.
We study the Langevin dynamics of the standard random heteropolymer model by mapping the problem to a supersymmetric field theory using the Martin-Siggia-Rose formalism. The resulting model is solved nonperturbatively employing a Gaussian variational approach. In constructing the solution, we assume that the chain is very long and impose the translational invariance which is expected to be pres...
متن کاملBreathing dynamics in heteropolymer DNA.
While the statistical mechanical description of DNA has a long tradition, renewed interest in DNA melting from a physics perspective is nourished by measurements of the fluctuation dynamics of local denaturation bubbles by single molecule spectroscopy. The dynamical opening of DNA bubbles (DNA breathing) is supposedly crucial for biological functioning during, for instance, transcription initia...
متن کاملSequence sensitivity of breathing dynamics in heteropolymer DNA.
We study the fluctuation dynamics of localized denaturation bubbles in heteropolymer DNA with a master equation and complementary stochastic simulation based on novel DNA stability data. A significant dependence of opening probability and waiting time between bubble events on the local DNA sequence is revealed and quantified for a biological sequence of the T7 bacteriophage. Quantitative agreem...
متن کاملHeteropolymer Folding
8 Heteropolymer Folding among the nite T landscape and the one at T = 0. One nds that the structure of the minima does not change much from T = 1 to T = 0, for example. The free energy landscape is quite stable. 16 is a SIMD parallel super-computer. In the tube version, the one we have used here, it has a theoretical speed of 6:5 GGops (and, as we will discuss , reaches an unusually high sustai...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Europhysics Letters (EPL)
سال: 1993
ISSN: 0295-5075,1286-4854
DOI: 10.1209/0295-5075/22/3/002